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Administration of nirmatrelvir-ritonavir has been used for patients with persistent SARS COV-2, since some studies suggest that the persistence of SARS-CoV-2 in tissues and especially in the intestinal microbiome and virome may be involved in the pathogenesis of L-C19 (250)

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doi:10.1016/j.mehy.2021.110736 [3] Veljaca M., Sladoljev D., Mildner B