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Hydroxocobalamin acetate ampoules, vitamin B12a. Red coloured solution for injection in the treatment for vitamin B12 deficiency. Accord Healthcare Stock Photo - Alamy

The G2-to-mitosis (G2/M) transition is driven by Cdk1 bound to M-cyclin (cyclin B), and the resulting cyclin B-Cdk1 complex phosphorylates numerous substrates required for mitotic progression 5

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Itaconic acid is a mammalian metabolite induced during macrophage activation