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Despite the poor permeability of the blood–brain barrier to mercury, prolonged exposure and slow elimination can lead to the accumulation of mercury ions in the central nervous system and cause neurotoxicity (8)

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Design: Analysis of cerebrospinal fluid obtained from children enrolled in an Institutional Review Board–approved, randomized, placebo-controlled trial of a combination of probenecid and N-acetylcysteine after severe traumatic brain injury (Trial Registration NCT01322009)