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If you eat before administration, particularly foods containing carbohydrates, insulin levels rise and partially inhibit the fat-releasing pathways AOD-9604 activates

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Size:300 cc

Drugs much smaller have low oral bioavailability due to difficulty in getting through the gut wall… Even if AOD9604 was only a small peptide, it would still be susceptible to enzymatic degradation in the gut, being derived as it is from a naturally occurring protein12

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