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Therefore, we cultured the extended simplified human intestinal microbiota [SIHUMIx, ( in vitro by using a continuous flow cultivation system and treated the microbes with mixtures of BPX (BPF, BPS), PFAS (PFBA, PFHxA, PFOA) or the combination of both chemical classes

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One hypothesis is that increased NNMT activity could influence NAD+ availability and cellular methylation in ways that contribute to age-associated metabolic changes