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For example, studies by Lindenbaum et al 38 and Healton et al 5 showed that up to 28% of patients with neuropsychiatric symptoms of B 12 deficiency can present with normal mean corpuscular volume (MCV), hematocrit (HCT), or both

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BBR is a chemically stable quaternary ammonium isoquinoline alkaloid, characterized by the molecular formula C 20 H 18 NO 4 and the molecular weight is 336.37 g/mol ( Despite its extremely low concentration in the bloodstream (Kheir et al., 2010), the pharmacological efficacy of BBR is closely associated with its extensive distribution across tissues

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